Female Hormone Imbalance Smith Chiro
Friday, January 14, 2011 13:46Estrogen Dominance in Pre-menopausal Women An article by Dr. Michael Lam There are two periods in a women’s life that her progesterone level is low – at puberty and again at peri-menopause ( the few years right before menopause). Between puberty and peri-menopause, the production of progesterone can go astray, leading to estrogen dominance as mentioned earlier. Between this period, estrogen dominance can also be the result of excessive external estrogen intake (from diet and environment) or internal estrogen production ( from obesity, birth control pills, or ovarian tumor). Two common causes are: A. Anovulation (lack of ovulation). Ovulation is the time of the month where an ovarian follicle releases an ovum (egg). Under normal condition, the released egg makes it way from the ovary to the uterus in preparation for fertilization. This usually happens from day 12 to day 14 of the menstrual cycle. After the egg is released, the empty follicle becomes the corpus luteum. This is the main factory where the production of progesterone takes place. When the follicles become dysfunctional, no eggs are released. This is called anovulation. If a woman is not ovulating, there would not be a corpus luteum and therefore no increased progesterone production. Laboratory measurement would show both a low estrogen and a low progesterone level. Many still have a seemingly normal menstrual cycle even if there is no ovulation. The lack of progesterone, however, leads to relative estrogen dominance and symptoms like PMS, mood swings, cramps, and tender breast. Anovulation is commonly caused by exposure of female embryos to environmental estrogen (also called xenobiotic or xenoestrogen) such as pesticides, plastic, and pollution. It is often related to a poor diet and stress. B. Luteal insufficiency. More frequent than anovulation, the egg is produced but the corpus luteum malfunctions. It just does not make enough progesterone. Laboratory measurements would show a high estrogen but low progesterone, and typical symptoms of estrogen dominance would arise. Without adequate progesterone, the chance of achieving pregnancy is reduced. Don’t forget that progesterone is what keeps the womb going and it nourishes the fetus.


